谭国欣 女 理学博士 副教授 硕士生导师

  2022年2月通过高层次人才引进到海南大学药学院工作。

  邮箱：tanguoxintgx@163.com

     1.教育背景

  2015.08-2021.09 沈阳药科大学 药剂学 博士（硕博连读）

  2010.09-2014.07 内蒙古医科大学 药学 学士

  2.科研情况

  主要致力于非病毒基因载体在眼部疾病中的应用和纳米制剂的研究，在Acta Biomaterialia、International Journal of Pharmaceutics等SCI期刊上发表研究性论文7篇，其中第一作者5篇。参与过国家自然科学基金面上项目、青年科学基金项目等。

     3.研究领域

  核酸药物递送和纳米药物递送

  4.社会兼职

  Acta Biomaterialia和Journal of Drug Delivery Science and Technology杂志审稿人

5.代表性项目

 [1].国家自然科学基金委员会，面上项目，81773670，基于AS1411与NLS的视网膜级联靶向非病毒基因载体构建及其抗CNV机制研究，2018-01-01至2021-12-31，48万元，在研，参与

[2].国家自然科学基金委员会，青年科学基金项目，81703455，基于多巴胺过表达调节的分子印迹-固相生物催化型给药系统的构建及评价，2018-01-01至2020-12-31，20.1万元，结题，参与

6.代表性成果

[1]. Guoxin Tan, Dandan Liu, Renfang Zhu, Hao Pan, Jiayang Li, Weisan Pan. A core-shell nanoplatform as a nonviral vector for targeted delivery of genes to the retina [J]. Acta Biomater, 2021,134: 605-620.

[2]. Guoxin Tan, Jinyu Li, Yiming Song, Yibin Yu, Dandan Liu, Weisan Pan. Phenylboronic acid-tethered chondroitin sulfate-based mucoadhesive nanostructured lipid carriers for the treatment of dry eye syndrome[J]. Acta Biomater, 2019,99: 350-362.

[3]. Guoxin Tan, Jiayang Li, Dandan Liu, Hao Pan, Renfang Zhu, Yue Yang, Weisan Pan. Amino acids functionalized dendrimers with nucleus accumulation for efficient gene delivery[J]. Int J Pharm, 2021,602: 120641.

[4]. Guoxin Tan, Shihui Yu, Jinyu Li, Weisan Pan. Development and characterization of nanostructured lipid carriers based chitosan thermosensitive hydrogel for delivery of dexamethasone[J]. Int J Biol Macromol, 2017,103: 941-947.

[5]. Guoxin Tan, Shihui Yu, Jinyu Li, Weisan Pan. Development and characterization of nanostructured lipid carriers based chitosan thermosensitive hydrogel for delivery of dexamethasone[J]. Int J Biol Macromol, 2017,103: 941-947.

[6]. Jinyu Li, Guoxin Tan, Bingchao Cheng, Dandan Liu, Weisan Pan. Transport mechanism of chitosan-N-acetylcysteine, chitosan oligosaccharides or carboxymethyl chitosan decorated coumarin-6 loaded nanostructured lipid carriers across the rabbit ocular[J]. Eur J Pharm Biopharm, 2017,120: 89-97.

[7]. Shihui Yu, Guoxin Tan, Dandan Liu, Xinggang Yang, Weisan Pan. Nanostructured lipid carrier (NLC)-based novel hydrogels as potential carriers for nepafenac applied after cataract surgery for the treatment of inflammation: design, characterization and in vitro cellular inhibition and uptake studies[J]. RSC Advances, 2017,7(27): 16668-16677.